People who have never used modern antibiotics showed to have developed antibiotic resistance gene, as researchers found out that an isolated tribe from South America has natural resistance to antibiotics.
A research published in the journal Science Advances has analyzed the bodily bacteria of a remote tribe from South America leading scientist to believe that the human’s body capacity to resist antibiotics has existed long before the development of antibiotic treatments.
The Yanomami are people living in isolated conditions in the mountain region of South Venezuela and they have been living there ever since their ancestors settled, almost 11,000 years ago. They had lived separated from the rest of the world until 2009 when they were discovered by researchers.
These people have shown to have the largest diversity of bacteria that was ever found in humans. Some of the microbes, have actually never been discovered in the human body before, explained researchers.
What was surprising to discover was the fact that the tribe possessed genes that were resistant to natural antibiotics which included those germs that have developed resistance to antibiotics produced synthetically, but these people have never taken man made antibiotics.
Scientists have tested bacteria collected from the Venezuelan tribe, to 23 different types of antibiotics and discovered that the medicine managed to kill every single one of them. Even so, further analysis has shown that the bacteria contained a hidden resistance that was set off when in contact with the antibiotics.
Exaggerated use of antibiotics used for treatments or for agriculture purposes is causing a world wide increase of germs who have developed resistance and strong medicine is losing its ability to kill them.
Our system contains trillions of microbes(microbiome) that live inside and outside of every area of our body and each of them has a role in the functioning and health of the human body, from controlling the immune system to digesting food.
It seems that the pre-modern humans had a most extended gamma of microbes and bacteria which had more diversified roles, comparing to the humans that have been affected by modern life and treatments, like modern antibiotics and processed diets, explained professor of immunology and pathology, Gautam Dantas from the Washington University, St.Louis.
Medicine professor Maria Dominguez-Bello from the Langone Medical Center from New York, stated that the explanation for the diminishing of microbial diversity in our bodies, might be the fact that certain diseases like diabetes, asthma, allergies and obesity have increased for the last 40 years.
She added that researchers have serious reasons to assume that there is something that has changed in the environment for the past decades that has expanded the occurring of this diseases, and that thing might have to do with our microbiome.
For the experiment, scientists have studied microbial samples from the mouth, intestines and skin taken from 34 of the Yanomami people which were compared to a group of people from the United States, a number of people from Malawi, South Africa and another tribe from Venezuela called the Guihabo.
The Yanomami people showed to have a doubled number of microbe diversity compared to U.S. people and 30%-40% than the people from Malawi and Guahibo.
Certain microbes possessed only by the Yanomami served to protect the body against developing kidney stones.
For the moment, researchers are not sure is this diverse microbiome found in the Yanomami, has a beneficial or negative impact on the health.
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