The study conducted by the University of Texas Medical Branch from Galveston has brought to light a discovery that reveals how a person who have gone through a transplant surgery can become protected against Alzheimer’s disease by the simple intake of anti-rejection drugs.
Scientists haven’t yet found a cure for Alzheimer’s disease, the neurodegenerative disorder which is mostly triggered in elderly people. Newly found evidence demonstrates that toxic protein contributes to a damaging effect on memory, in people who are troubled by this disease.
Thus, managing to keep at bay this type of toxicity can help develop an efficacious strategy of treatment.
Memory formation and brain cells communication are gravely impaired by the elevation of the enzyme called Calcineurin, which normally regulates these functions. The interesting discovery is that high levels of Calcineurin were found in patients who suffer from Alzheimer’s disease.
The University of Texas Medical Branch’s scientists have recently conducted a research on 2,644 patients from Texas area, who underwent a transplant surgery and who will have to take anti-rejection medications for the rest of their lives.
Analyzing the findings from the research data, scientists discovered a significantly lower rate of dementia and Alzheimer’s disease at the patients who received an organ and were thus taking anti-rejection drugs.
The researchers went further than the Texas area, and they have been able to acquire similar results.
“Calcineurin inhibition has a protective effect on the development and possible progression and even reversal of Alzheimer’s disease”Professor and Vice Chair for Research, Giulio Taglialatela declared.
On that note, along with his team, he is presently undergoing research work on designing treatment strategies that involve the use of low doses of Calcineurin inhibitors, thus hoping to keep in check the formation of the terrible affliction.
The study has not yet been published but it is expected to be so in due course, by the middle of this summer and it will be found online in the 7th issue of the Journal of Alzheimer’s Disease.
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